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Nasal Delivery Of Weight-Loss Hormone Simplifies Breathing Issues In Sleeping Mice

Whole testing on mice, researchers at Johns Hopkins Medicine have added to evidence that a hormone best recognized for assisting control body weight and hunger may also ease breathing issues felt during sleep more efficiently when offered via the nose. Even though clinical tests employing the hormone, dubbed as leptin, are not yet imminent, the investigators claim that their success giving it via the noses of test animals might assist them develop simpler-to-use treatments for users with sleep-associated breathing issues such as sleep apnea.

The results were posted online in the American Journal of Respiratory and Critical Care Medicine. Leptin, a hormone that was first verified in 1994 and created by fat cells, targets the appetite center of brain, assisting to control the appetite. “Even though the potential of leptin for curbing overeating and treating obesity failed to materialize in human tests, its significance in the respiratory system has activated new rounds of therapeutic promises,” claims senior author of the study and professor at the Johns Hopkins University School of Medicine for critical care & pulmonary medicine, and, Vsevolod Polotsky.

Speaking of obesity, a study claims that nighttime junk food cravings and snacking might add up to unhealthful eating behaviors. In addition, it might represent a possible link between obesity and poor sleep. They study was conducted by sleep researchers from University of Arizona Health Sciences.

The research was carried out through a phone-based and countrywide study of 3,105 people from 23 metropolitan regions of the US. Participants were asked if they frequently ate a nighttime snack. Moreover, they asked if the lack of sleep made them crave junk food. In addition, they were also asked about their current health issues and sleep quality. Almost 60% of people reported frequent nighttime snacking and 2/3rd claimed that lack of sleep resulted them in craving for additional junk food.

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